IkB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kB in the central nervous system

1 Department of Neuropathology, University of Freiburg, Breisacher Str. 64, D-79106 Freiburg, Germany 2 Department of Neuropathology, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, D-37099 Göttingen, Germany 3 EMBL Mouse Biology Programme, I-00016 Monterotondo, Italy 4 Department of Molecular Biomedical research, VIB and Ghent University, Technologiepark 927, B-9052 Ghent, Belgium 5 Department of Pathology and Immunology, Division of Clincial Pathology, Geneva University Hospital and University of Geneva, Rue Michel-Servet 1, 1211 Geneva, Switzerland 6 The Miami Project to Cure Paralysis, Miller School of Medicine, University of Medicine, Miami, FL 33136, USA 7 1st Medical Department, Johannes Gutenberg University Mainz, D-55131 Mainz, Germany 8 Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe-University, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany 9 Neuropsychiatry and Laboratory of Molecular Psychiatry, Charité-Universitätsmedizin Berlin, Schumannstr. 20-21, D-10117 Berlin, Germany 10 Institute of Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Str. 47, D-50674 Cologne, Germany